Alterations of serum metabolic profile in major depressive disorder: A case-control study in the Chinese population

Figure 1 Metabolomic analysis of serum samples from major depressive disorder and healthy control groups. A: 2D partial least squares discriminant analysis scores plot of top 2 components; B: Overview of the performance of the top 5 components; C: The heatmap of representative metabolites to distinguish major depressive disorder and healthy control. ¹The model with three components has the highest Q2 value, thus demonstrating the best prediction performance. HC: Healthy control; MDD: Major depressive disorder; FA: Fatty acid; CMPF: 3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid.