©The Author(s) 2025.
World J Psychiatry. Dec 19, 2025; 15(12): 113433
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.113433
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.113433
Figure 4 Chronic unpredictable stress model.
The chronic unpredictable stress model is a widely used model in animal research. In this model, animals are exposed to a series of unpredictable stressors, which may include noise, changes in lighting, and adverse temperatures. These stressors vary in time and intensity, simulating the unpredictable stressors that occur in real life.
- Citation: Lu XX, Tang H, Li XH. Selecting an appropriate stress model of depression in rodents. World J Psychiatry 2025; 15(12): 113433
- URL: https://www.wjgnet.com/2220-3206/full/v15/i12/113433.htm
- DOI: https://dx.doi.org/10.5498/wjp.v15.i12.113433