Effect of cognitive behavioral therapy on cancer-related fatigue and psychological status in ovarian cancer patients: A meta-analysis

Table 4 Meta-regression analysis of depression and anxiety

Analysis	Depression				Anxiety
	Estimate (SE)	95%CI	P value		Estimate (SE)	95%CI	P value
Patients characteristics
Age	0.02 (0.14)	-0.26 to 0.29	0.8838		-0.06 (0.04)	-0.14 to 0.03	0.1733
China	-0.91 (0.59)	-2.06 to 0.24	0.1229
United States	-0.22 (0.65)	-1.48 to 1.05	0.7388		-1.28 (0.56)	-2.36 to -0.19	0.0217a
United Kingdom	-0.16 (0.67)	-1.46 to 1.15	0.8127		-0.85 (0.59)	-2.01 to 0.31	0.1497
Intervention methods
CBT/exercise	-0.49 (0.43)	-1.33 to 0.34	0.2485
I-CBT	0.98 (0.55)	-0.10 to 2.05	0.0767		0.06 (0.53)	-0.98 to 1.10	0.9092
Traditional-CBT	0.23 (0.41)	-0.57 to 1.02	0.5727		-0.27 (0.40)	-1.06 to 0.51	0.4966
Assessment scales
CES-D	0.68 (0.69)	-0.66 to 2.03	0.3179	STAI-Y	0.88 (0.64)	-0.37 to 2.14	0.1704
HADS	0.98 (0.61)	-0.21 to 2.16	0.1073	HADS	0.06 (0.53)	-0.98 to 1.10	0.9092
PHQ-9	0.53 (0.53)	-0.50 to 1.56	0.3157	SAS	-0.40 (0.40)	-1.19 to 0.40	0.3266
SDS	-0.22 (0.45)	-1.10 to 0.66	0.6292
Nurse-led	-0.56 (0.28)	-1.12 to -0.00	0.0486a		1.15 (0.55)	0.08 to 2.22	0.0359a

^aP < 0.05.

CI: Confidence interval; CBT: Cognitive behavioral therapy; I-CBT: Internet-based cognitive behavioral therapy; CES-D: Center for epidemiologic studies-depression scales; HADS: Hospital anxiety-depression scale; PHQ-9: Patient health questionnaire-9; SDS: Self-rating depression scale; STAI-Y: State trait anxiety inventory scale; SAS: Self-rating anxiety scale.