Effect of cognitive behavioral therapy on cancer-related fatigue and psychological status in ovarian cancer patients: A meta-analysis

Table 2 Characteristics of the six included studies[12-17]

Ref.	Country	Study design	Multi-center	Registered	Record patient time	Ovarian cancer patients	Age (T)	Age (C)	Sample size		Intervention (T)	Intervention (C)	Outcome
									T (n)	C (n)
Frangou et al[12]	United Kingdom	RCT	Yes	Yes	November 2013 to January 2018	Primary or relapsed epithelial OC	58.1 ± 9.46	60.9 ± 10.2	34	33	CBT	Standard care	Depression, QoL
Zhou et al[13]	China	RCT	No	NR	January 2018 to March 2019	Meets the diagnostic criteria for OC	58.64 ± 13.82	60.23 ± 15.78	37	36	CBT + conventional nursing	Conventional nursing	Cancer-related fatigue, depression, anxiety, sleep quality, QoL
Zhang et al[14]	China	RCT	No	NR	November 2014 to November 2015	Ages of 18 and 80 with OC	NR	NR	33	34	CBT + exercise	Usual care	Cancer-related fatigue, depression, sleep quality
Petzel et al[15]	United States	RCT	Yes	Yes	September 2012 to February 2013	Stage III/IV or recurrent (any stage) epithelial OC	59.6 ± 10.0	55.5 ± 8.4	16	12	Website based on CBT	Control website	Distress, depression, anxiety
Moonsammy et al[16]	Canada	RCT	No	NR	March 2011 to July 2011	Newly diagnosed with OC	52.7 ± 12.1	57.8 ± 12.0	3	5	CBT	Surveillance	Cancer-related fatigue, depression, anxiety
Rost et al[17]	United States	RCT	No	NR	NR	Women with stage III or IV OC	56	56	15	16	ACT	Treatment as usual	Distress, depression, anxiety, QoL, acceptance

T: Treatment group; C: Control group; RCT: Randomized controlled trial; NR: Not report; OC: Ovarian cancer; CBT: Cognitive behavioral therapy; ACT: Acceptance and commitment therapy; QoL: Quality of life.