Investigating the pharmaceutical substances and action mechanisms of Changmaxifeng granules against tic disorders

Table 4 Results of Kyoto Encyclopedia of Genes and Genomes enrichment

Description	Gene ratio	Count	-log10 (P value)	-log10 (q value)
Neuroactive ligand-receptor interaction	52/203	52	25.8	23.78
Pathways of neurodegeneration - multiple diseases	43/203	43	13.7	12.38
Alzheimer disease	36/203	36	11.9	10.68
cAMP signaling pathway	32/203	32	15.7	14.18
Calcium signaling pathway	27/203	27	10.8	9.7
Serotonergic synapse	26/203	26	17.9	16.2
MAPK signaling pathway	24/203	24	6.6	6.1
Estrogen signaling pathway	21/203	21	10.9	9.8
Chemical carcinogenesis - reactive oxygen species	21/203	21	7.1	6.5
Ras signaling pathway	20/203	20	6	5.6
Cholinergic synapse	18/203	18	9.8	8.8
Chemokine signaling pathway	18/203	18	6.1	5.7
T cell receptor signaling pathway	17/203	17	9.47	8.5
Neurotrophin signaling pathway	17/203	17	8.5	7.7
Phospholipase D signaling pathway	17/203	17	7	6.5
Thyroid hormone signaling pathway	16/203	16	7.5	6.9
Dopaminergic synapse	16/203	16	7	6.4
Apoptosis	16/203	16	6.8	6.3
C-type lectin receptor signaling pathway	15/203	15	7.6	6.9
Sphingolipid signaling pathway	15/203	15	6.7	6.2
B cell receptor signaling pathway	14/203	14	8	7.3
TNF signaling pathway	14/203	14	6.3	5.8
Endocrine resistance	13/203	13	6.2	5.8
VEGF signaling pathway	12/203	12	7.9	7.2
Gap junction	12/203	12	5.9	5.5
IL-17 signaling pathway	12/203	12	5.6	5.3
Toll-like receptor signaling pathway	12/203	12	5.1	4.9
Fc epsilon RI signaling pathway	11/203	11	6.2	5.8
Longevity regulating pathway - multiple species	10/203	10	5.7	5.34