Investigating the pharmaceutical substances and action mechanisms of Changmaxifeng granules against tic disorders

Table 3 Significantly enriched Gene Ontology biological processes of the target genes

GO term	Subgroup	-log10 (P value)	Count	-log10 (q value)
Modulation of chemical synaptic transmission	Biological process	31.3	47	28.23
Regulation of trans-synaptic signaling	Biological process	31.3	47	28.23
Response to xenobiotic stimulus	Biological process	28.8	44	26.4
Regulation of membrane potential	Biological process	27.1	43	24.8
Signal release	Biological process	23.0	40	21.0
Cellular divalent inorganic cation homeostasis	Biological process	21.6	40	19.7
Cellular calcium ion homeostasis	Biological process	21.9	39	19.9
Calcium ion homeostasis	Biological process	21.5	39	19.6
Calcium ion transport	Biological process	21.0	37	19.2
Muscle system process	Biological process	19.2	36	17.5
Synaptic membrane	Cellular component	31.4	44	29.0
Postsynaptic membrane	Cellular component	29.8	38	27.8
Presynapse	Cellular component	20.3	38	18.7
Neuronal cell body	Cellular component	19.7	37	18.2
Membrane raft	Cellular component	19.2	31	17.8
Membrane microdomain	Cellular component	19.2	31	17.8
Intrinsic component of synaptic membrane	Cellular component	19.6	24	18.1
Distal axon	Cellular component	14.2	24	13.0
Transmembrane transporter complex	Cellular component	11.1	24	10.0
Transporter complex	Cellular component	10.6	24	9.6
Neurotransmitter receptor activity	Molecular function	36.5	33	34.0
Metal ion transmembrane transporter activity	Molecular function	10.9	26	9.3
Ion channel activity	Molecular function	10.6	26	9.1
Channel activity	Molecular function	9.7	26	8.3
Passive transmembrane transporter activity	Molecular function	9.6	26	8.3
Gated channel activity	Molecular function	11.5	24	9.8
Amide binding	Molecular function	10.0	24	8.5
Cation channel activity	Molecular function	10.5	23	9.0
G protein-coupled amine receptor activity	Molecular function	25.0	20	22.8
Peptide binding	Molecular function	8.7	20	7.4

GO: Gene Ontology.