Psychological adjustment differences in ovarian cancer patients receiving different treatment modalities and their clinical significance

Table 3 Effects of psychological intervention on treatment adherence, quality of life, and psychological status in ovarian cancer patients, mean ± SD/ n (%)

Assessment category	Indicator	Pre-intervention	Post-intervention	Change	Statistics	P value
Overall effects (n = 76)	Complete adherence	51 (67.1)	68 (89.8)	+22.7%	χ2 = 11.37	< 0.01
	QoL global score	60.3 ± 7.8	75.9 ± 8.4	+15.6	t = 11.86	< 0.01
	Functional domain	58.7 ± 7.5	77.6 ± 8.3	+18.9	t = 15.27	< 0.001
	SAS score	53.8 ± 7.2	44.1 ± 6.8	-9.7	t = 8.36	< 0.001
	SDS score	55.6 ± 7.4	45.2 ± 6.9	-10.4	t = 9.24	< 0.001
Treatment group effects
Combined therapy group (n = 29)	Anxiety incidence	17 (58.5)	8 (28.0)	-30.5%	χ2 = 16.32	< 0.001
	Depression incidence	18 (62.2)	10 (36.4)	-25.8%	χ2 = 14.76	< 0.001
	SAS score	56.8 ± 7.5	45.3 ± 6.9	-11.5	t = 10.52	< 0.001
	SDS score	59.1 ± 7.8	47.4 ± 7.1	-11.7	t = 11.08	< 0.001
	QoL score	58.3 ± 7.6	75.2 ± 8.3	+16.9	t = 12.34	< 0.001
Chemotherapy group (n = 20)	Anxiety incidence	10 (50.0)	5 (25.0)	-25.0%	χ2 = 10.24	< 0.01
	Depression incidence	11 (55.0)	7 (35.0)	-20.0%	χ2 = 8.75	< 0.01
	SAS score	54.9 ± 7.3	44.8 ± 6.8	-10.1	t = 8.73	< 0.001
	SDS score	56.3 ± 7.5	46.2 ± 7.0	-10.1	t = 8.92	< 0.001
	QoL score	60.8 ± 7.7	75.6 ± 8.3	+14.8	t = 10.46	< 0.001
Surgery group (n = 12)	Anxiety incidence	4 (33.3)	2 (16.7)	-16.6%	χ2 = 5.62	0.023
	Depression incidence	5 (41.7)	3 (25.0)	-16.7%	χ2 = 5.83	0.021
	SAS score	52.1 ± 7.0	43.6 ± 6.7	-8.5	t = 6.54	< 0.01
	SDS score	53.4 ± 7.1	44.8 ± 6.8	-8.6	t = 6.82	< 0.01
	QoL score	61.8 ± 7.9	75.7 ± 8.4	+13.9	t = 9.47	< 0.001
Targeted therapy group (n = 15)	Anxiety incidence	4 (26.7)	2 (13.5)	-13.2%	χ2 = 4.83	0.034
	Depression incidence	5 (33.3)	3 (21.6)	-11.7%	χ2 = 4.55	0.042
	SAS score	49.8 ± 6.8	42.3 ± 6.5	-7.5	t = 5.68	< 0.01
	SDS score	51.3 ± 7.0	43.5 ± 6.6	-7.8	t = 5.93	< 0.01
	QoL score	64.2 ± 8.1	77.5 ± 8.6	+13.3	t = 9.21	< 0.001

QoL: Quality of Life; SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale.