Psychological adjustment differences in ovarian cancer patients receiving different treatment modalities and their clinical significance

Table 2 Changes in psychological status of ovarian cancer patients at different treatment time points, mean ± SD

Treatment group	Assessment scale	Baseline	Month 3	t value (vs baseline)	P value (vs baseline)	Month 6	t value (vs month 3)	P value (vs month 3)
Surgery group (n = 78)	SAS score	46.3 ± 6.2	52.1 ± 7.0b	t = 5.24	< 0.01	47.9 ± 6.5a	t = 3.42	0.02
	SDS score	47.6 ± 6.3	53.4 ± 6.8b	t = 5.36	< 0.01	48.8 ± 6.6a	t = 3.81	0.03
Chemotherapy group (n = 65)	SAS score	45.8 ± 6.5	55.7 ± 7.3c	t = 8.52	< 0.001	53.4 ± 7.1	t = 1.86	0.07
	SDS score	46.9 ± 6.1	56.9 ± 7.4c	t = 8.94	< 0.001	55.2 ± 7.3	t = 1.43	0.16
Targeted therapy group (n = 61)	SAS score	45.5 ± 6.1	49.8 ± 6.8b	t = 4.16	< 0.01	45.7 ± 6.3a	t = 3.68	0.02
	SDS score	47.2 ± 6.2	51.2 ± 6.5b	t = 3.85	< 0.01	46.9 ± 6.4a	t = 3.96	0.01
Combined therapy group (n = 82)	SAS score	47.2 ± 6.6	58.9 ± 7.5c	t = 9.35	< 0.001	56.8 ± 7.4	t = 1.56	0.12
	SDS score	48.4 ± 6.7	60.5 ± 7.6c	t = 9.86	< 0.001	59.3 ± 7.5	t = 0.87	0.39
Between-group comparison	SAS score	F = 0.86; P = 0.463	F = 18.43; P < 0.001			F = 24.67; P < 0.001
	SDS score	F = 0.92; P = 0.432	F = 20.35; P < 0.001			F = 25.82; P < 0.001

^aP < 0.05 vs month 3.

^bP < 0.01 vs baseline.

^cP < 0.001 vs baseline.

SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale.