Neural correlates of attentional switching dysfunction in major depressive disorder: Evidence from an event-related potential study with a dual-task paradigm

Table 4 The mean amplitude and latencies of event-related potential components

Variables1	MDD (n = 29)						HC (n = 29)
	Fz		Cz		Pz		Fz		Cz		Pz
	Amplitude	Latency	Amplitude	Latency	Amplitude	Latency	Amplitude	Latency	Amplitude	Latency	Amplitude	Latency
N100
500	-4.4 (3.1)	71.6 (14.3)	-2.5 (3.0)	61.4 (14.9)	-0.2 (2.5)	57.2 (22.9)	-5.3 (2.5)	73.7 (13.4)	-3.2 (2.0)	65.2 (14.8)	-0.6 (1.6)	55.2 (14.6)
1000	-4.5 (3.1)	70.6 (12.2)	-2.5 (2.8)	61.5 (13.8)	-0.2 (2.0)	58.9 (22.2)	-5.2 (2.5)	76.1 (16.5)	-3.1 (2.1)	64.7 (15.2)	-0.1 (2.3)	56.4 (20.5)
1500	-4.6 (2.9)	73.1 (14.5)	-2.6 (2.8)	62.9 (15.3)	-0.1 (2.3)	57.4 (19.5)	-5.2 (2.7)	74.3 (14.2)	-3.1 (2.3)	66.3 (15.7)	-0.5 (1.9)	57.7 (21.0)
P200
500	-4.4 (5.9)	178.6 (40.7)	-0.9 (4.9)	181.3 (41.7)	1.9 (4.0)	199.9 (47.2)	-4.0 (4.5)	173.0 (35.7)	-0.5 (3.5)	176.8 (37.0)	1.3 (2.7)	190.3 (45.9)
1000	-4.6 (6.1)	177.7 (41.8)	-1.1 (4.8)	179.0 (41.5)	1.7 (3.7)	204.5 (46.5)	-3.3 (4.6)	171.7 (32.5)	-0.2 (3.7)	178.0 (37.2)	1.6 (3.0)	186.7 (44.3)
1500	-4.5 (5.2)	178.3 (41.3)	-1.0 (4.5)	177.4 (38.9)	1.9 (3.7)	200.2 (46.3)	-3.5 (4.4)	177.7 (38.5)	0.1 (3.7)	186.7 (42.7)	1.7 (3.0)	192.3 (45.5)
P300
500	-7.1 (9.5)	278.8 (40.5)	-3.3 (6.3)	276.1 (42.4)	1.3 (4.7)	291.2 (51.4)	-9.6 (9.3)	274.6 (44.1)	-3.6 (6.2)	293.0 (57.4)	0.9 (4.9)	311.0 (59.0)
1000	-7.0 (9.4)	270.8 (34.2)	-3.3 (6.3)	282.6 (49.7)	1.3 (4.6)	295.5 (51.3)	-9.2 (9.7)	271.5 (42.3)	-3.5 (6.3)	293.0 (57.6)	1.0 (5.0)	302.6 (60.5)
1500	-7.3 (9.1)	277.2 (41.5)	-3.5 (6.2)	275.0 (43.5)	1.2 (4.6)	285.2 (47.6)	-9.6 (10.1)	265.4 (28.8)	-3.3 (6.5)	284.1 (54.1)	1.0 (5.0)	304.3 (54.7)
LPP
500	-9.3 (10.6)	435.8 (64.3)	-5.2 (6.6)	410.3 (52.9)	-0.3 (4.7)	405.1 (46.8)	-13.7 (11.5)	407.3 (56.5)	-5.8 (7.6)	419.8 (60.8)	-0.1 (5.8)	411.1 (53.3)
1000	-9.6 (10.8)	425.3 (60.6)	-5.3 (7.0)	412.8 (54.2)	-0.2 (4.9)	413.5 (53.2)	-14.0 (12.7)	413.6 (63.0)	-6.0 (8.0)	422.6 (57.3)	-0.3 (6.2)	423.4 (59.6)
1500	-9.5 (10.1)	423.0 (63.3)	-5.3 (6.8)	410.3 (55.2)	-0.2 (4.8)	409.2 (50.6)	-14.2 (11.8)	407.7 (58.1)	-5.7 (7.5)	425.8 (62.5)	-0.1 (5.4)	424.2 (61.8)
N100
Angry	-2.8 (2.6)	70.1 (16.3)	-1.7 (2.2)	61.9 (15.2)	0.1 (1.7)	59.0 (22.1)	-3.1 (2.2)	71.9 (14.8)	-2.0 (1.6)	63.2 (16.3)	-0.5 (1.3)	58.1 (20.1)
Happy	0.7 (2.7)	75.9 (24.0)	-0.5 (1.9)	66.6 (20.3)	0.3 (1.5)	65.4 (28.1)	-0.9 (2.5)	71.7 (21.6)	-0.9 (1.6)	66.3 (22.9)	-0.3 (1.2)	69.8 (30.7)
Neutral	-1.0 (2.4)	74.1 (23.7)	-1.0 (1.6)	72.8 (25.8)	-0.1 (1.2)	65.0 (28.1)	-1.0 (2.4)	68.7 (20.2)	-1.0 (1.4)	66.9 (23.2)	-0.6 (1.2)	65.9 (29.0)
P200
Angry	-1.9 (3.4)	179.1 (40.8)	0.2 (3.2)	185.0 (40.8)	2.0 (2.7)	214.0 (42.7)	-1.1 (2.6)	177.3 (34.6)	0.8 (2.3)	188.9 (40.3)	1.6 (1.9)	204.3 (42.4)
Happy	2.1 (3.2)	192.8 (27.1)	2.5 (2.9)	200.5 (32.4)	3.6 (2.4)	224.3 (30.0)	2.5 (3.6)	192.2 (23.2)	2.8 (2.7)	196.6 (23.0)	2.7 (2.0)	225.3 (27.3)
Neutral	1.8 (3.1)	194.7 (28.0)	2.0 (2.9)	196.9 (29.7)	3.2 (2.3)	222.0 (29.5)	2.3 (3.7)	194.6 (24.7)	2.4 (2.6)	201.3 (26.1)	2.3 (2.0)	221.7 (28.3)
P300
Angry	-3.7 (5.6)	274.1 (39.7)	-1.5 (4.1)	279.9 (47.2)	1.9 (3.1)	289.3 (49.3)	-5.2 (5.8)	276.6 (44.6)	-1.3 (4.0)	294.8 (58.5)	1.6 (3.4)	308.5 (58.6)
Happy	0.7 (4.1)	290.1 (57.9)	1.3 (3.9)	295.9 (62.3)	4.0 (2.7)	319.5 (61.6)	0.2 (3.7)	289.4 (50.6)	1.7 (3.2)	306.4 (58.3)	3.8 (3.5)	317.6 (51.2)
Neutral	0.4 (3.6)	292.5 (56.9)	1.0 (3.6)	301.2 (60.9)	3.9 (2.5)	324.9 (56.6)	-0.2 (3.7)	297.2 (59.9)	1.5 (3.1)	311.0 (63.1)	3.6 (3.0)	337.7 (51.8)
LPP
Angry	-5.3 (6.8)	423.0 (63.6)	-2.9 (4.6)	410.7 (56.2)	0.7 (3.3)	411.1 (57.3)	-8.6 (7.7)	404.4 (57.0)	-3.1 (5.2)	413.9 (59.8)	0.7 (4.0)	405.6 (54.6)
Happy	-0.1 (5.0)	440.7 (68.1)	0.7 (4.4)	445.3 (67.0)	3.1 (2.9)	416.9 (59.8)	-2.2 (4.5)	410.9 (60.9)	0.5 (3.4)	426.6 (71.0)	2.8 (3.2)	416.2 (66.5)
Neutral	0.0 (4.1)	450.3 (66.4)	0.7 (4.1)	441.8 (64.4)	3.3 (2.9)	424.7 (61.2)	-2.2 (4.3)	401.1 (49.8)	0.7 (3.7)	424.9 (66.6)	3.0 (3.4)	405.3 (52.0)

¹All values presented in microvolts (μV).

MDD: Patients with major depressive disorder; HC: Healthy controls; Fz: Frontal; Cz: Central; Pz: Parietal.