Relationship between anxiety and depression, dyspnea severity, and pulmonary function in connective tissue disease-associated interstitial lung disease

Figure 4 Multi-pathway mechanism of anxiety and depression affecting connective tissue disease-associated interstitial lung disease pulmonary function. ↑Positive effect (Green), ↓Negative effect (Orange), the thickness of the arrow is in direct proportion to the magnitude of the effect amount, hazard ratio value is based on time-varying covariate Cox model. GAD-7: Generalized anxiety disorder-7; PHQ-9: Patient health questionnaire-9; HRCT: High-resolution computed tomography; HR: Hazard ratio.