Relationship between anxiety and depression, dyspnea severity, and pulmonary function in connective tissue disease-associated interstitial lung disease

doi:10.5498/wjp.v15.i12.110916

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Dec 19, 2025; 15(12): 110916
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.110916

Table 7 Correlation matrix between psychological state scores and clinical indicators

Indicators	FVC (%)	DLCO (%)	CRP	ESR	mMRC	GAD-7	PHQ-9
FVC (%)	1
DLCO (%)	0.712^b	1
CRP	-0.489^b	-0.524^b	1
ESR	-0.437^b	-0.471^b	0.586^b	1
mMRC	-0.518^b	-0.493^b	0.442^b	0.498^b	1
GAD-7	-0.426^b	-0.451^b	0.372^b	0.339^a	0.534^b	1
PHQ-9	-0.409^b	-0.437^b	0.356^b	0.329^a	0.519^b	0.871^b	1

^aP < 0.05.

^bP < 0.001.

P < 0.05 indicates significant differences. FVC: Forced vital capacity; DLCO: Diffusing capacity of the lungs for carbon monoxide; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; mMRC: Modified medical research council; GAD-7: Generalized anxiety disorder-7; PHQ-9: Patient health questionnaire-9.

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Citation: Zhu ZJ, Liu KL, Qu HR. Relationship between anxiety and depression, dyspnea severity, and pulmonary function in connective tissue disease-associated interstitial lung disease. World J Psychiatry 2025; 15(12): 110916
URL: https://www.wjgnet.com/2220-3206/full/v15/i12/110916.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i12.110916

Zhu ZJ, Liu KL, Qu HR. Relationship between anxiety and depression, dyspnea severity, and pulmonary function in connective tissue disease-associated interstitial lung disease. World J Psychiatry 2025; 15(12): 110916 [PMID: 41357912 DOI: 10.5498/wjp.v15.i12.110916]

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