Relationship between anxiety and depression, dyspnea severity, and pulmonary function in connective tissue disease-associated interstitial lung disease

doi:10.5498/wjp.v15.i12.110916

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Dec 19, 2025; 15(12): 110916
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.110916

Table 6 Indicators of oxygenation function

Indicators	At enrollment	Week 4	Week 12	Week 24	F value	P value
SpO₂ (%)	88.74 ± 5.13	90.32 ± 4.88	91.45 ± 4.59	92.13 ± 4.21	15.238	< 0.001
PaO₂ (mmHg)	58.96 ± 8.27	62.87 ± 7.56	65.23 ± 7.11	67.45 ± 6.85	18.427	< 0.001
PaCO₂ (mmHg)	40.15 ± 5.42	39.82 ± 5.16	39.58 ± 5.21	39.34 ± 5.10	1.254	0.292
Hypoxemia cases	35	28	22	17	8.013	0.045

P < 0.05 indicated significant difference. SpO₂: Peripheral capillary oxygen saturation; PaO₂: Partial pressure of arterial oxygen; PaCO₂: Partial pressure of arterial carbon dioxide.

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Citation: Zhu ZJ, Liu KL, Qu HR. Relationship between anxiety and depression, dyspnea severity, and pulmonary function in connective tissue disease-associated interstitial lung disease. World J Psychiatry 2025; 15(12): 110916
URL: https://www.wjgnet.com/2220-3206/full/v15/i12/110916.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i12.110916

Zhu ZJ, Liu KL, Qu HR. Relationship between anxiety and depression, dyspnea severity, and pulmonary function in connective tissue disease-associated interstitial lung disease. World J Psychiatry 2025; 15(12): 110916 [PMID: 41357912 DOI: 10.5498/wjp.v15.i12.110916]

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