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©The Author(s) 2025.
World J Psychiatry. Dec 19, 2025; 15(12): 110290
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.110290
Table 2 Psychological interventions for anxiety after percutaneous coronary intervention and their effects/applications in cardiac patients
Sources
Intervention types
Primary targets
Response patterns
Roles/functions
Potential applications
Intervention-based approaches
Psycho-cardiologyCognitive therapyCatastrophic interpretationsIncreased (moderate)Correct misattribution of normal post-PCI sensationsTreatment of acute anxiety
Exposure therapyCardiac-related avoidance behaviorsIncreased (moderate)Rebuild self-efficacy and functional capacityLong-term rehabilitation
Relaxation trainingAutonomic arousalIncreased (moderate)Reduce physiological markers of anxietyAcute phase management
PsychoeducationKnowledge deficitsIncreased (moderate)Increase understanding of normal recovery processPrevention of anxiety development
Environmental approachesA-FLORA-ACS ProtocolHospital environmentIncreased (moderate)/increased (moderate)Provide positive attentional focus during recoveryAdjunctive treatment
Sound therapyStress hormonesIncreased (moderate)Reduce autonomic arousal and improve sleep qualityInpatient management
Guided imageryRuminationIncreased (moderate)Redirect attention from cardiac concernsSelf-management tool
Cardiac rehabilitationSupervised exercisePhysical deconditioningIncreased (moderate)Counter avoidance behaviors through graded exposureComprehensive recovery
Group-based programsSocial isolationIncreased (moderate)Normalize experiences through peer supportCost-effective delivery
Stress managementGlobal anxietyIncreased (moderate)Develop coping strategies for cardiac stressorsPrevention of major adverse cardiovascular event
Domains of anxiety
Physiological anxietyBiofeedbackHeart rate variabilityIncreased (moderate)Improve autonomic regulationTargeted intervention
Progressive muscle relaxationSomatic tensionIncreased (moderate)Reduce physical manifestations of anxietySelf-management
Cognitive anxietyCBT protocolsWorry and ruminationIncreased (moderate)Restructure cardiac-related cognitionsChronic anxiety treatment
Mindfulness-based interventionsAttentional biasIncreased (moderate)Develop nonjudgmental awareness of sensationsTherapeutic target
Behavioral anxietyActivity schedulingActivity avoidanceIncreased (moderate)Gradual reintroduction of avoided activitiesFunctional improvement
Motivational interviewingTreatment adherenceIncreased (moderate)Enhance engagement with recovery behaviorsMedication adherence
Cardiac-specific anxietyHeart-focused anxiety treatmentCardiac vigilanceIncreased (moderate)Reduce hypervigilance to bodily sensationsSpecialized protocol
Cardiorespiratory fitness trainingExercise anxietyIncreased (moderate)Build confidence in cardiac capacityPhysiological improvement
Special populations
Gender-specificWomen's recovery programsCaregiving concernsIncreased (moderate)Address role disruption and dependency fearsGender-focused care
Men's cardiac groupsAutonomy threatsIncreased (moderate)Address occupational and self-efficacy concernsEngagement enhancement
Comorbid depressionIntegrated treatment protocolsAnhedonia and anxietyIncreased (moderate)Target overlapping neurobiological mechanismsDual-diagnosis approach
Behavioral activationWithdrawal behaviorsIncreased (moderate)Increase positive reinforcementTreatment resistance
Older adultsAge-adapted protocolsMemory and learningIncreased (moderate)Accommodate cognitive changes in older patientsGeriatric cardiology
Social prescribingIsolationIncreased (moderate)Connect patients with community resourcesSustainable support


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