Psychocardiological impact of depression on medication adherence, ventricular function, and readmission in heart failure: A retrospective cohort study

doi:10.5498/wjp.v15.i12.109437

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Psychiatry. Dec 19, 2025; 15(12): 109437
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.109437

Table 6 Multivariable Cox regression analysis of independent predictors for 1-year cardiovascular event readmission

Variable	Hazard ratio	95% confidence interval	P value
Age	1.028	1.005-1.052	0.016
LVEF	0.969	0.947-0.991	0.009
PHQ-9 score	1.059	1.025-1.094	< 0.001
β-blocker use	0.732	0.562-0.953	0.024
NT-proBNP	1.018	1.003-1.033	0.021
Psychotherapy	1.447	0.912-2.296	0.112
NYHA class IV	1.611	1.102-2.354	0.037
Worsening CHF at admission	1.723	1.103-2.694	0.031

LVEF: Left ventricular ejection fraction; PHQ-9: Patient Health Questionnaire-9; NT-proBNP: N-terminal pro-B-type natriuretic peptide; NYHA: New York Heart Association; CHF: Congestive heart failure.

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Citation: Mao FG, Tang YL, Wang XY, Jin X, Fan JY. Psychocardiological impact of depression on medication adherence, ventricular function, and readmission in heart failure: A retrospective cohort study. World J Psychiatry 2025; 15(12): 109437
URL: https://www.wjgnet.com/2220-3206/full/v15/i12/109437.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i12.109437

Mao FG, Tang YL, Wang XY, Jin X, Fan JY. Psychocardiological impact of depression on medication adherence, ventricular function, and readmission in heart failure: A retrospective cohort study. World J Psychiatry 2025; 15(12): 109437 [PMID: 41357921 DOI: 10.5498/wjp.v15.i12.109437]

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