Computerized cognitive behavioral therapy with sertraline in schizophrenia with depressive episodes: A 12-week randomized controlled trial

Table 4 Comparison of MATRICS consensus cognitive battery scores between experimental and control groups

Outcome	Pre-treatment (baseline)					Post-treatment (12 weeks)
	Experimental group (n = 34)	Control group (n = 34)	MD (95%CI)	P value	Cohen’s d1	Experimental group (n = 34)	Control group (n = 34)	MD (95%CI)	P value	Cohen’s d1
ProcSpeed	42.35 ± 9.07	42.21 ± 8.89	0.15 (-4.20, 4.49)	0.946	-	47.03 ± 7.85	42.97 ± 8.35	4.06 (0.13, 7.98)	0.043	0.50
AttnVig	41.65 ± 9.21	39.71 ± 10.10	1.94 (-2.74, 6.62)	0.411	-	45.76 ± 8.25	44.76 ± 6.58	1.00 (-2.61, 4.61)	0.583	-
WorkMem	40.15 ± 9.22	41.06 ± 7.88	-0.91 (-5.07, 3.24)	0.663	-	46.62 ± 7.96	42.74 ± 8.91	3.88 (-0.21, 7.97)	0.063	-
VerbLrn	42.00 ± 9.95	41.94 ± 10.25	0.06 (-4.83, 4.95)	0.981	-	46.09 ± 8.57	43.50 ± 5.56	2.59 (-0.91, 6.08)	0.144	-
VisLrn	41.44 ± 8.77	40.29 ± 8.22	1.15 (-2.97, 5.26)	0.580	-	46.56 ± 6.33	46.47 ± 6.76	0.09 (-3.08, 3.26)	0.956	-
ProbSolv	42.62 ± 6.56	43.24 ± 11.08	-0.62 (-5.63, 4.39)	0.806	-	46.00 ± 7.60	44.79 ± 8.11	1.21 (-2.60, 5.01)	0.529	-
SocCog	33.38 ± 9.02	34.26 ± 8.89	-0.88 (-5.22, 3.45)	0.686	-	39.82 ± 6.92	34.91 ± 7.21	4.91 (1.49, 8.33)	0.006	0.70
Total	40.47 ± 8.96	40.38 ± 8.82	0.09 (-4.22, 4.39)	0.967	-	45.35 ± 7.57	42.85 ± 6.87	2.50 (-1.00, 6.00)	0.159	-

¹Effect sizes are shown when t-tests are significant; small effect (> 0.2), medium effect (> 0.5), large effect (> 0.8).

95%CI: 95% confidence interval; ProcSpeed: Processing speed; AttnVig: Attention vigilance; WorkMem: Working memory; VerbLrn: Verbal learning; VisLrn: Visual learning; ProbSolv: Reasoning and problem solving; SocCog: Social cognition.