Computerized cognitive behavioral therapy with sertraline in schizophrenia with depressive episodes: A 12-week randomized controlled trial

Table 1 Computerized cognitive behavioral therapy modules

Module	Module title	Content description
1	Psychoeducation and self-assessment	Introduction to the structure and objectives of CCBT. Includes completion of mood and cognition self-assessments, and identification of target symptoms and treatment goals
2	Relaxation and stress regulation	Training in abdominal breathing, progressive muscle relaxation, and guided imagery. Includes multimedia demonstrations and interactive practice tasks
3	Behavioral activation	Education on the relationship between behavior and mood. Activity scheduling tasks to promote engagement in enjoyable or meaningful routines, with daily tracking tools
4	Cognitive restructuring	Explanation to negative automatic thoughts and common cognitive distortions. Includes interactive exercises to identify and challenge maladaptive beliefs
5	Homework assignments	Review and reinforcement of prior modules through structured tasks. Examples include mood logs, thought records, and activity diaries, with feedback and reminders
6	Relapse prevention	Review of core skills. Identification of early warning signs for relapse. Development of personalized prevention plans. Includes future-oriented coping strategies

CCBT: Computerized cognitive behavioral therapy.