Effect of amino acid-balanced diet-based nutritional-psychological intervention on muscle wasting and quality of life in cirrhosis patients

Table 2 The scores of each dimension of the quality-of-life assessment questionnaire for the two groups of patients before and after the intervention (points), mean ± SD

Group	n	Time	Fatigue	Emotional function	Abdominal symptoms	Systemic symptoms	Activity	Worry	Total score	P value (between-group)
Observation group	65	Before intervention	3.84 ± 0.91	3.72 ± 0.89	3.52 ± 0.85	3.78 ± 0.90	3.61 ± 0.87	3.91 ± 0.93	22.38 ± 2.185	> 0.05
		Intervention for 3 months	4.78 ± 1.02	4.56 ± 0.97	4.36 ± 0.95	4.75 ± 1.02	4.56 ± 0.98	4.85 ± 1.02	27.86 ± 2.4351	< 0.001
		Intervention 6 months	5.28 ± 1.05	5.12 ± 1.02	4.85 ± 1.02	5.25 ± 1.05	5.02 ± 1.02	5.35 ± 1.05	30.87 ± 2.5352	< 0.001
		Overall within-group	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
Control group	65	Before intervention	3.88 ± 0.93	3.76 ± 0.91	3.56 ± 0.87	3.82 ± 0.92	3.65 ± 0.89	3.95 ± 0.95	22.63 ± 2.234	> 0.05
		Intervention for 3 months	4.18 ± 0.95	4.05 ± 0.93	3.85 ± 0.90	4.12 ± 0.95	3.95 ± 0.92	4.25 ± 0.97	24.40 ± 2.2951	< 0.001
		Intervention 6 months	4.48 ± 0.97	4.35 ± 0.95	4.12 ± 0.92	4.42 ± 0.97	4.25 ± 0.95	4.55 ± 0.98	26.17 ± 2.3442	< 0.001
		Overall within-group	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001

¹Significant difference compared with the same group before intervention.

²Significant difference compared with the same group 3 months after intervention and compared with the same group before intervention.

Intergroup comparisons were performed using independent samples t-tests; intra-group comparisons were performed using repeated measures analysis of variance, with post hoc tests using Bonferroni correction.