Psychiatric sequelae following aneurysmal subarachnoid hemorrhage: Insights from a high-volume neurosurgical center in northern China

Table 7 Univariate and multivariate analysis of depression symptoms at follow-up

Variables	Univariate			Multivariate
	P value	Exp	95%CI	P value	Exp	95%CI
Gender	< 0.001	1.803	1.407-2.309	0.029	1.429	1.037-1.970
Age > 60	< 0.001	1.759	1.379-2.242	< 0.001	0.581	0.451-0.749
Smoking	< 0.001	0.569	0.429-0.753	0.484	0.877	0.607-1.267
Alcohol abuse	< 0.001	< 0.001	0.375-0.697	0.087	0.711	0.481-1.051
Hypertension	0.514	0.924	0.729-1.171
Diabetes	0.653	0.899	0.564-1.432
Hyperlipidemia	0.666	1.097	0.721-1.669
Multiple aneurysms	0.003	1.813	1.229-2.675	0.003	1.844	1.234-2.757
Family history of cerebral bleeding	0.741	1.117	0.579-2.154
HH grade 4 and 5	0.472	1.181	0.750-1.861
WFNS grade 4 and 5	0.719	1.064	0.758-1.494
MFS grade 3 and 4	0.774	1.036	0.813-1.321
Posterior aneurysm1	0.079	1.419	0.960-2.097	0.018	1.652	1.091-2.502
Surgical clipping	0.001	1.477	1.165-1.873	0.187	1.189	0.920-1.537
Clinical outcomes2	0.006	1.951	1.212-3.141	0.001	2.264	1.375-3.730
Function-improvement3	0.001	1.481	1.163-1.886	< 0.001	1.604	1.242-2.071

¹Posterior aneurysm means the ruptured aneurysms locates on posterior circulation.

²Clinical outcomes represent favorable functional outcomes identified as modified Rankin Scale ≤ 2.

³Function-improvement means modified Rankin Scale score descended at follow-up than at discharge.

HH: Hunt and Hess; WFNS: World Federation of Neurosurgical Societies; mFS: Modified Fisher Scale; CI: Confidence interval.