Brain region and cell specificity of B4GALT6 in mice with depressive-like behavior: A pilot study

Figure 4 The hippocampal CA2 region of depressive-like mice have an increased density of B4GALT6⁺NeuN⁺ cells. A: Statistical results of the number of B4GALT6 and GFAP co-labeled cells (B4GALT6⁺GFAP⁺) in the hippocampal CA2 region, with no significant difference between the two groups; B: Statistical results of the number of B4GALT6 and NeuN co-labeled cells (B4GALT6⁺NeuN⁺) in the hippocampal CA2 region, indicating that the number of such cells in the lipopolysaccharides (LPS) group was significantly higher than that in the phosphate-buffered saline (PBS) group; C: Statistical results of the number of B4GALT6 and IBA1 co-labeled cells (B4GALT6⁺IBA1⁺) in the hippocampal CA2 region, with no significant difference between the two groups; D: Immunofluorescence co-localization images of the hippocampal CA2 region, displaying the co-localization of DAPI (blue), B4GALT6 (red) with NeuN (green), GFAP (green), and IBA1 (green) in the PBS group and LPS group. The number of B4GALT6⁺NeuN⁺ cells was higher in the LPS group compared to the PBS group. LPS: Lipopolysaccharides; PBS: Phosphate-buffered saline.