Brain region and cell specificity of B4GALT6 in mice with depressive-like behavior: A pilot study

Figure 3 Brains from depressive-like mice have increased B4GALT6⁺IBA1⁺cell density within the hippocampal CA1 region. A: Statistical results of the number of B4GALT6 and GFAP co-labeled cells (B4GALT6⁺GFAP⁺) in the hippocampal CA1 region, with no significant difference between the two groups; B: Statistical results of the number of B4GALT6 and NeuN co-labeled cells (B4GALT6⁺NeuN⁺) in the hippocampal CA1 region, with no significant difference between the two groups; C: Statistical results of the number of B4GALT6 and IBA1 co-labeled cells (B4GALT6⁺IBA1⁺) in the hippocampal CA1 region, with a significant increase in the lipopolysaccharides (LPS) group compared to the phosphate-buffered saline (PBS) group; D: Immunofluorescence co-localization images of the hippocampal CA1 region, showing the co-localization of DAPI (cell nuclei, blue), B4GALT6 (red) with IBA1 (green), GFAP (green), and NeuN (green) in the PBS group and LPS group, respectively. The number of B4GALT6⁺IBA1⁺ cells in the LPS group was increased compared to the PBS group. LPS: Lipopolysaccharides; PBS: Phosphate-buffered saline.