©The Author(s) 2025.
World J Psychiatry. Oct 19, 2025; 15(10): 109425
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.109425
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.109425
Figure 2 B4GALT6 expression in hippocampus, PrL and V1 of visual cortex increased in depressive-like behavior mice.
A: Schematic diagram of the experimental procedure; B: Sucrose preference test outcomes [phosphate-buffered saline (PBS) vs lipopolysaccharides (LPS), 86.20 ± 9.97 vs 64.14 ± 9.1, P = 8.00 × 10-6]; C: Results of the tail suspension test (PBS vs LPS, 93.42 ± 45.96 vs 133 ± 39.26, P = 0.030); D: Results of the forced swimming test (PBS vs LPS, 50.75 ± 18.14 vs 70.14 ± 23.4, P = 0.037); E: Western blot of B4GALT6 expression; F: Statistical results of Western blot for B4GALT6. FST: Forced swimming test; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; HIP: Hippocampus; IF: Immunofluorescence; LPS: Lipopolysaccharides; PBS: Phosphate-buffered saline; SPT: Sucrose preference test; TST: Tail suspension test; WB: Western blot.
- Citation: Zhang SN, Luan D, Sheng BY, Xie B, Xiao L. Brain region and cell specificity of B4GALT6 in mice with depressive-like behavior: A pilot study. World J Psychiatry 2025; 15(10): 109425
- URL: https://www.wjgnet.com/2220-3206/full/v15/i10/109425.htm
- DOI: https://dx.doi.org/10.5498/wjp.v15.i10.109425