Suicide attempt predictors among adolescents exhibiting non-suicidal self-injury: A six-week follow-up open study

Table 6 Pre- and post-treatment cytokine levels in the whole sample

Inflammatory cytokine	Pre-treatment	Post-treatment	Z	P value
TNF-α	4.05 (3.10, 4.67)	2.98 (2.11, 3.53)	-4.72	< 0.001b
IL-6	3.43 (1.28, 3.58)	1.42 (1.11, 1.62)	-4.615	< 0.001b
IL-10	1.04 (0.87, 1.21)	0.85 (0.56, 1.04)	-4.082	< 0.001b
IL-1	4.00 (2.59, 3.40)	2.58 (2.36, 2.77)	-4.306	< 0.001b
IFN-γ	12.43 (10.90, 13.03)	25.41 (9.30, 12.17)	-2.561	0.010a
IL-4	3.13 (2.02, 3.32)	7.02 (4.80, 8.87)	-5.401	< 0.001b
IL-17	3.42 (2.69, 3.79)	3.34 (3.05, 4.05)	-0.657	0.511
IL-2	5.82 (4.39, 7.24)	5.44 (4.37, 6.76)	-1.570	0.116
IFN-α	1.95 (1.70, 2.00)	2.27 (2.00, 2.46)	-4.814	< 0.001b
IL-12	137.66 (129.96, 150.45)	127.03 (111.56, 132.41)	-2.219	0.026a

^aP < 0.05.

^bP < 0.001.

Wilcoxon signed-rank tests (non-parametric) were used to compare inflammatory cytokine levels before and after treatment. Data are presented as median, with Z and P values reported. TNF: Tumor necrosis factor; IL: Interleukin; IFN: Interferon.