KAT7/HMGN1 signaling epigenetically induces tyrosine phosphorylation-regulated kinase 1A expression to ameliorate insulin resistance in Alzheimer’s disease

Figure 2 KAT7 alleviated Alzheimer’s disease-induced neurological damages in vivo. A: Western blotting assay to evaluate the expression of KAT7 and Aβ in brain tissues; B: Immunofluorescence staining of microtubule-associated protein 2 in brain tissues; C: Evaluation of oxidative biomarkers reactive oxygen species in brain tissues; D: Evaluation of oxidative biomarkers malondialdehyde in brain tissues; E: Evaluation of oxidative biomarkers SOD activity in brain tissues. ^bP < 0.01. MDA: Malondialdehyde; ROS: Reactive oxygen species; AD: Alzheimer’s disease; NC: Negative control; MAP2: Microtubule-associated protein 2.