Exosomal miR-320e through wnt2targeted inhibition of the Wnt/β-catenin pathway allevisate cerebral small vessel disease and cognitive impairment

Figure 1 Construction and bioinformatics analysis of differentially expressed miRNA libraries. A: Volcano diagram showing that miRNA-320e was significantly downregulated; B: High-throughput sequencing of plasma exosomes showed that the expression of miR-320e was significantly downregulated; C: Bioinformatics suggested the biological processes involved in differentially expressed miRNAs. Further information was shown in the Supplementary Material.