Brain-derived neurotrophic factor, sex hormones and cognitive decline in male patients with schizophrenia receiving continuous antipsychotic therapy

Table 3 Correlations between sex hormones and brain-derived neurotrophic factor levels in all subjects¹

	BDNF
	r	P value2	P value3	P value4
FSH (ng/mL)	0.068	0.467	0.638	NS
LH (ng/mL)	-0.256	0.007	0.011	NS
E2 (ng/mL)	0.343	< 0.001	0.001	S.
P (ng/mL)	0.074	0.459	0.173	NS
T (ng/mL)	-0.215	0.032	0.055	NS
PRL (ng/mL)	-0.267	0.004	0.04	NS

¹Pearson product moment.

²Before adjusting for confounding factors.

³After adjusting for confounding factors (body mass index).

⁴Bonferroni correction was applied (a new = 0.05/5 = 0.01).

NS: Not significant; S.: Significant; FSH: Follicle-stimulating hormone; LH: Luteinizing hormone; E2: Estradiol; P: Progesterone; T: Testosterone; PRL: Prolactin.