Clinical and Translational Research
Copyright ©The Author(s) 2023.
World J Psychiatry. Jan 19, 2023; 13(1): 15-35
Published online Jan 19, 2023. doi: 10.5498/wjp.v13.i1.15
Table 5 Results of repeated measures analysis of variance for outcome variables
Dependent variable
Independent variable
Degrees of freedom
F value
P value
Partial eta squared (variance explained; i.e., effect size)
Bonferroni adjusted pairwise comparisons
HADS depressionTimepoint (within subjects)2, 3612.81< 0.0010.42Baseline (mean 11.21 SD 4.28) vs post-treatment (mean 7.11, SD 3.99), P = 0.004Baseline vs follow-up (mean 7.21, SD 4.99), P = 0.001 Post treatment vs follow-up, P = 1.0
Employment (between subjects)1, 179.730.0060.36Employed vs unemployed mean difference1 -4.55 (95%CI: -7.62 to -1.47); employed have lower mean score at all three time points
Employment X time point (within subjects)2, 340.060.940.004NANANA
HADS AnxietyTimepoint (within subjects)2, 369.93< 0.0010.36Baseline (mean 14.53 SD 4.01) vs post-treatment (mean 11.05, SD 3.40), P = 0.003Baseline vs follow-up (mean 11.21, SD 4.05), P = 0.001Post treatment vs follow-up, P = 0.831
WHO disability scale totalTimepoint (within subjects)1.29, 14.1826.7320.0160.382Baseline (mean 66.58 SD 40.13) vs post-treatment (mean 44.42, SD 32.35), P = 0.034Baseline vs follow-up (mean 38.75, SD 26.499), P = 0.014Post treatment vs follow-up, P = 0.194
Living alone (between subjects)1, 108.990.0130.47Living alone vs with someone mean difference1 51.9 (95%CI: 13.33 to 90.47); living alone have higher score at all three timepoints
Living alone X timepoint (within subjects)1.21, 12.0720.3920.5810.042NANANA
Employment (between subjects)1, 108.680.0150.47Employed vs unemployed mean difference1 -44.26 (95%CI: -77.62 to -10.79); employed have lower mean score at all three time points
Employment X Time point (within subjects)1.32, 13.1822.9920.10.232NANANA
CORE totalTimepoint1.25, 18.72214.9820.0010.52Baseline (mean 76.81, SD 23.26) vs post-treatment (mean 49.25, SD 27.00), P = 0.002Baseline vs follow-up (mean 52.19, SD 25.72), P < 0.001Post treatment vs follow-up, P = 0.404
CORE total mean with riskTimepoint1.25, 18.72214.9820.0010.52Baseline (mean 2.26, SD 0.68) vs post-treatment (mean 1.45, SD 0.79), P = 0.002Baseline vs follow-up (mean 1.53, SD 0.76), P < 0.001Post treatment vs follow-up, P = 0.404
CORE Total mean without riskTimepoint1.24, 18.66216.58< 0.0010.532Baseline (mean 2.62, SD 0.71) vs post-treatment (mean 1, SD 0.87), P = 0.001Baseline vs follow-up (mean 1.77, SD 0.79), P < 0.001Post treatment vs follow-up, P = 0.523
CORE risk meanTimepoint2, 361.830.1750.09Baseline (mean 0.48, SD 0.75) vs post-treatment (mean 0.26, SD 0.55), P = 0.109Baseline vs follow-up (mean 0.39, SD 0.77), P = 0.418Post treatment vs follow-up, P = 0.096
CORE symptoms meanTimepoint2, 3291.10< 0.0010.54Baseline (mean 2.81, SD 0.77) vs post-treatment (mean 1.76, SD 1.03), P < 0.001Baseline vs follow-up (mean 1.91, SD 0.89), P < 0.001Post treatment vs follow-up, P = 0.317
CORE functioning meanTimepoint1.25, 19.9227.260.010.31Baseline (mean 2.25, SD 0.88) vs post-treatment (mean 1.61, SD 0.86), P = 0.016Baseline vs follow-up (mean 1.65, SD 0.83), P = 0.009Post treatment vs follow-up, P = 0.692
CORE well being meanTimepoint2, 3620.41< 0.0010.53Baseline (mean 2.82, SD 0.67) vs post-treatment (mean 1.68, SD 0.68), P < 0.001Baseline vs follow-up (mean 1.76, SD 0.87), P < 0.001Post treatment vs follow-up, P = 0.61
BSI totalTimepoint2, 366.500.0080.26Baseline (mean 22.11, SD 11.40) vs post-treatment (mean 19.05, SD 10.23), P < 0.066Baseline vs follow-up (mean 16.47, SD 11.10), P < 0.008Post treatment vs follow-up, P = 0.041