Depressive disorder and antidepressants from an epigenetic point of view

doi:10.5498/wjp.v12.i9.1150

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Sep 19, 2022; 12(9): 1150-1168
Published online Sep 19, 2022. doi: 10.5498/wjp.v12.i9.1150

Table 5 Histone deacetylase classification and localization

HDAC category	HDAC class	HDAC type	Localization
Zinc-dependent HDACs	Class I	HDACs 1, 2, 3, 8	Localized in nucleus
	Class II	HDACs 4, 5, 7, 9, 10	Pass between nucleus and cytoplasm
	Class II	HDAC6	Localized in the cytoplasm
	Class IV	HDAC11
NAD-dependent SIRTs	Class III	SIRTs 1, 2, 6 and 7	Localized in the nucleus
NAD-dependent SIRTs	Class III	SIRTs 3, 4 and 5	Localized in the mitochondria

HDACs: Histone deacetylases; NAD-dependent sirtuins: Nicotinamide-adenine-dinucleotide–dependent sirtuins; SIRTs: Sirtuins.

Citation: Šalamon Arčan I, Kouter K, Videtič Paska A. Depressive disorder and antidepressants from an epigenetic point of view. World J Psychiatry 2022; 12(9): 1150-1168
URL: https://www.wjgnet.com/2220-3206/full/v12/i9/1150.htm
DOI: https://dx.doi.org/10.5498/wjp.v12.i9.1150