Differential aberrant connectivity of precuneus and anterior insula may underpin the diagnosis of schizophrenia and mood disorders

doi:10.5498/wjp.v11.i12.1274

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatr. Dec 19, 2021; 11(12): 1274-1287
Published online Dec 19, 2021. doi: 10.5498/wjp.v11.i12.1274

Table 4 Connections significantly different from zero in the depressive syndrome group

Connections	Mean	P value
dACC→DLPFC	0.146	0.029^a
Pc→DLPFC	-0.239	0.002^b
VLPFC⊃	-0.185	0.002^b
dACC→VLPFC	0.180	0^c
aI→VLPFC	-0.250	0.002^b
Pc→VLPFC	-0.177	0.007^b
DLPFC→dACC	0.212	0.004^b
VLPFC→dACC	-0.181	0.02^a
dACC⊃	-0.160	0.007^b
Pc→dACC	-0.228	0.006^b
aI⊃	-0.216	0.003^b
DLPFC→Pc	0.090	0.047^a
VLPFC→Pc	0.133	0.029^a
dACC→Pc	0.090	0.049^a
aI→Pc	-0.284	0^c

^aP < 0.05.

^bP < 0.01.

^cP < 0.001.

⊃: Self-inhibitory connection; DLPFC: Dorsolateral prefrontal cortex; VLPFC: Ventrolateral prefrontal cortex; IFG: Inferior frontal gyrus; dACC: Dorsal anterior cingulate cortex; AI: Anterior insula; Pc: Precuneus.

Citation: Aryutova K, Paunova R, Kandilarova S, Stoyanova K, Maes MH, Stoyanov D. Differential aberrant connectivity of precuneus and anterior insula may underpin the diagnosis of schizophrenia and mood disorders. World J Psychiatr 2021; 11(12): 1274-1287
URL: https://www.wjgnet.com/2220-3206/full/v11/i12/1274.htm
DOI: https://dx.doi.org/10.5498/wjp.v11.i12.1274