Systems biology applications to study mechanisms of human immunodeficiency virus latency and reactivation

Figure 1 Summary of methods used across gene expression profiling studies in the field of human immunodeficiency virus latency and eradication. Identification of DEGs and functional analysis of GO terms and pathways enriched for DEGs are the methods that are most commonly used across studies. Network-based analyses are used in a subset of studies; while methods that consolidate host gene expression with other data types (e.g., proteomics or HIV expression data) are scarce. DEGs: Differentially expressed genes; GO: Gene ontology; HIV: Human immunodeficiency virus.