Tuberculosis and hematopoietic stem cell transplant: Review of a difficult and often underestimated problem

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World Journal of Clinical Infectious Diseases

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2220-3176

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Infect Dis. Nov 25, 2013; 3(4): 70-78
Published online Nov 25, 2013. doi: 10.5495/wjcid.v3.i4.70

Table 2 Salient aspects for diagnosing tuberculosis in a hematopoietic stem cell transplantation recipient

Test	Sensitivity (%)¹	Specificity (%)¹	Indicates
TB skin test	72	35	LTBI or active TB
Acid-fast bacillus	50-80	98	Infection
Nucleic acid amplification test	80-98	95-99	Infection
Culture	70-90	98	Active TB
Serology	20-70	47-81	Active TB or infection
Interferon gamma release assays	50-99	85-99	LTBI or active TB
Chest radiography	47-73	76	Probable active TB

¹These numbers are influenced by the epidemiological situation. LTBI: Latent tuberculosis infection; TB: Tuberculosis.

Citation: García-Elorriaga G, Rey-Pineda GD. Tuberculosis and hematopoietic stem cell transplant: Review of a difficult and often underestimated problem. World J Clin Infect Dis 2013; 3(4): 70-78
URL: https://www.wjgnet.com/2220-3176/full/v3/i4/70.htm
DOI: https://dx.doi.org/10.5495/wjcid.v3.i4.70

García-Elorriaga G, Rey-Pineda GD. Tuberculosis and hematopoietic stem cell transplant: Review of a difficult and often underestimated problem. World J Clin Infect Dis 2013; 3(4): 70-78 [DOI: 10.5495/wjcid.v3.i4.70]

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