Tuberculosis and hematopoietic stem cell transplant: Review of a difficult and often underestimated problem

Table 2 Salient aspects for diagnosing tuberculosis in a hematopoietic stem cell transplantation recipient

Test	Sensitivity (%)1	Specificity (%)1	Indicates
TB skin test	72	35	LTBI or active TB
Acid-fast bacillus	50-80	98	Infection
Nucleic acid amplification test	80-98	95-99	Infection
Culture	70-90	98	Active TB
Serology	20-70	47-81	Active TB or infection
Interferon gamma release assays	50-99	85-99	LTBI or active TB
Chest radiography	47-73	76	Probable active TB

¹These numbers are influenced by the epidemiological situation. LTBI: Latent tuberculosis infection; TB: Tuberculosis.