Indocyanine green doped with chitosan nanoparticles based antimicrobial photodynamic therapy in periodontitis patients: A randomized clinical trial

doi:10.5493/wjem.v16.i1.117125

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Clinical Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Exp Med. Mar 20, 2026; 16(1): 117125
Published online Mar 20, 2026. doi: 10.5493/wjem.v16.i1.117125

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Figure 1 Preparation of indocyanine green-doped chitosan nanoparticles. A: Chitosan powder from shrimp shells 75% (deacetylated) (LOBA CHEMIE PVT. LTD.); B: Indocyanine Green Powder (Tokyo Chemical Industry Co., Ltd); C: Chitosan nanoparticles and indocyanine green dye is being mixed in magnetic stirrer; D: Digital pH meter showing pH of 4.8 of the mixed dye; E: Mixed photosensitizer is proceeded for lyophilization; F: 100 mg of indocyanine green-doped chitosan nanoparticles and 1000 mL of distilled water; G: Stirred with stirrer; H: Photosensitizer solution stored in amber coloured bottle to protect it from natural light; I: Photosensitizer solution loaded in 3 mL disposable syringe.

Citation: Raj SC, Sen S, Baral D, Mohanty D, Tabassum S, Sil S, Sahu M. Indocyanine green doped with chitosan nanoparticles based antimicrobial photodynamic therapy in periodontitis patients: A randomized clinical trial. World J Exp Med 2026; 16(1): 117125
URL: https://www.wjgnet.com/2220-315x/full/v16/i1/117125.htm
DOI: https://dx.doi.org/10.5493/wjem.v16.i1.117125

Raj SC, Sen S, Baral D, Mohanty D, Tabassum S, Sil S, Sahu M. Indocyanine green doped with chitosan nanoparticles based antimicrobial photodynamic therapy in periodontitis patients: A randomized clinical trial. World J Exp Med 2026; 16(1): 117125 [PMID: 41883436 DOI: 10.5493/wjem.v16.i1.117125]

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