Indocyanine green doped with chitosan nanoparticles based antimicrobial photodynamic therapy in periodontitis patients: A randomized clinical trial

Table 12 Comparison of mean modified sulcus bleeding scores between the groups at different time intervals

Modified sulcus bleeding index		Number	Mean	SD	t	P value
Baseline	aPDT with CNPs-ICG + SRP	30	2.04	0.44	0.52	0.6
	Conventional SRP	30	1.98	0.53		NS
1 month	aPDT with CNPs-ICG + SRP	30	0.48	0.36	-0.63	0.52
	Conventional SRP	30	0.54	0.42		NS
3 months	aPDT with CNPs-ICG + SRP	30	1.104	0.2	-0.787	0.43
	Conventional SRP	30	1.15	0.27		NS

Statistically significant using paired t-test. CNPs-ICG: Indocyanine green-doped chitosan nanoparticles; aPDT: Antimicrobial photodynamic therapy; SRP: Scaling and root planning; NS: Not significant.