Very low-density lipoprotein and the human health

doi:10.5493/wjem.v16.i1.117024

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Exp Med. Mar 20, 2026; 16(1): 117024
Published online Mar 20, 2026. doi: 10.5493/wjem.v16.i1.117024

Table 2 Summary of endocrinology effect on very low-density lipoprotein

Disorder/syndrome	Impact due to VLDL	Ref.
Cushing syndrome	Enhanced production	[61]
Exogenous cortisol	Decrease in degradation and enhanced adipose lipolysis	[62]
Aldosterone	Stimulation of aldosterone secretion	[65-67]
Growth hormone deficiency	Enhanced secretion and decline in clearance	[61]
Growth hormone treatment	Increased adipose lipolysis and increased clearance	[61]
Hypothyroidism	Decreased degradation with enhanced secretion	[73,74]
Androgen	Androgen-deprivation treatment: Enhanced concentration; transgender males with testosterone treatment: Enhanced concentration	[80-82]
Polycystic ovary syndrome	Enhanced concentration	[84]
Estrogen/progesterone therapy	Enhanced concentration	[85,86]
Prolactinoma	Uncertain	[94-96]

VLDL: Very low-density lipoprotein.

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Citation: Bharadwaj A, Taneja M, Dubey S, Saxena A. Very low-density lipoprotein and the human health. World J Exp Med 2026; 16(1): 117024
URL: https://www.wjgnet.com/2220-315x/full/v16/i1/117024.htm
DOI: https://dx.doi.org/10.5493/wjem.v16.i1.117024

Bharadwaj A, Taneja M, Dubey S, Saxena A. Very low-density lipoprotein and the human health. World J Exp Med 2026; 16(1): 117024 [PMID: 41883448 DOI: 10.5493/wjem.v16.i1.117024]

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