Effects of olopatadine hydrochloride on substance P concentrations in nasal secretions and nasal symptoms

doi:10.5493/wjem.v16.i1.116584

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Exp Med. Mar 20, 2026; 16(1): 116584
Published online Mar 20, 2026. doi: 10.5493/wjem.v16.i1.116584

Table 1 Classification of the severity of allergic rhinitis symptoms

Severity		Paroxysmal sneezing or rhinorrhea¹
Severity		4 (++++)	3 (+++)	2 (++)	1 (+)	0 (-)
Nasal blockage	4 (++++)	Most severe	Most severe	Most severe	Most severe	Most severe
	3 (+++)	Most severe	Severe	Severe	Severe	Severe
	2 (++)	Most severe	Severe	Moderate	Moderate	Moderate
	1 (+)	Most severe	Severe	Moderate	Mild	Mild
	0 (-)	Most severe	Severe	Moderate	Mild	No symptoms

¹Select more severe one, sneezing or rhinorrhea.

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Citation: Katagiri F, Hatoyama-Tanaka S, Watanabe T, Takayanagi R, Suzuki M, Yamada Y. Effects of olopatadine hydrochloride on substance P concentrations in nasal secretions and nasal symptoms. World J Exp Med 2026; 16(1): 116584
URL: https://www.wjgnet.com/2220-315x/full/v16/i1/116584.htm
DOI: https://dx.doi.org/10.5493/wjem.v16.i1.116584

Katagiri F, Hatoyama-Tanaka S, Watanabe T, Takayanagi R, Suzuki M, Yamada Y. Effects of olopatadine hydrochloride on substance P concentrations in nasal secretions and nasal symptoms. World J Exp Med 2026; 16(1): 116584 [PMID: 41883453 DOI: 10.5493/wjem.v16.i1.116584]

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