Antidiabetic effects of Gymnema sylvestre and metformin co-therapy in a type 2 diabetic rat model

doi:10.5493/wjem.v16.i1.116252

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World Journal of Experimental Medicine

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2220-315x

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Exp Med. Mar 20, 2026; 16(1): 116252
Published online Mar 20, 2026. doi: 10.5493/wjem.v16.i1.116252

Table 1 Induction of diabetes (pre-treatment data), mean ± SD

Group	Weight (g; baseline)	Weight (g; day 0)	FBG (mg/dL; day 0)
NC	163.16 ± 9.95	265.83 ± 21.77	101.16 ± 12.78
DC	163.16 ± 6.64	302.83 ± 56.02	476.00 ± 80.88^a
Met	158.16 ± 5.38	235.50 ± 22.98	461.50 ± 13.50^a
GS	154.66 ± 4.84	269.50 ± 32.77	448.66 ± 10.26^a
Met + GS	156.00 ± 6.54	280.16 ± 24.01	436.33 ± 27.78^a

^aP < 0.05 vs normal control.

NC: Normal control; DC: Diabetic control; Met: Metformin; GS: Gymnema sylvestre; FBG: Fasting blood glucose.

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Citation: Kodiyatar A, Mishra A, Dhakad MS, Roy V, Beg MMA, Rai N. Antidiabetic effects of Gymnema sylvestre and metformin co-therapy in a type 2 diabetic rat model. World J Exp Med 2026; 16(1): 116252
URL: https://www.wjgnet.com/2220-315x/full/v16/i1/116252.htm
DOI: https://dx.doi.org/10.5493/wjem.v16.i1.116252

Kodiyatar A, Mishra A, Dhakad MS, Roy V, Beg MMA, Rai N. Antidiabetic effects of Gymnema sylvestre and metformin co-therapy in a type 2 diabetic rat model. World J Exp Med 2026; 16(1): 116252 [PMID: 41883441 DOI: 10.5493/wjem.v16.i1.116252]

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