Abnormalities of liver sinusoidal endothelial cells in primary biliary cholangitis

Figure 2 Time points expression in EA. hy926 cells after incubation with serum from primary biliary cholangitis and chronic hepatitis C virus patients compared to controls considered as 1.0. Each bar represents the mean ± SD of 5 experiments. A: Endothelin 1 expression; B: Endothelin 2 expression; C: Endothelin 3 expression; D: Endothelin receptor A expression; E: Endothelin receptor B expression. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. NS: Not significant; ET: Endothelin; PBC: Primary biliary cholangitis; HCV: Hepatitis C virus; ENDRA: Endothelin receptor A; ENDRB: Endothelin receptor B.