Cardiac amyloidosis: From diagnosis to therapeutics breakthroughs

doi:10.5493/wjem.v16.i1.112270

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Exp Med. Mar 20, 2026; 16(1): 112270
Published online Mar 20, 2026. doi: 10.5493/wjem.v16.i1.112270

Table 2 Perugini scoring system for cardiac amyloid imaging interpretation

Perugini score	Cardiac uptake	Bone uptake	Interpretation
0	Absent	Normal	No evidence of cardiac amyloid deposition
1	Mild, less than bone uptake	Normal	Low-grade uptake, non-specific
2	Moderate	Reduced	Suggestive of transthyretin cardiac amyloidosis
3	Strong	Mild or absent	Highly suggestive of transthyretin cardiac amyloidosis

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Citation: Bouziane M, Moufid O, Habbal R. Cardiac amyloidosis: From diagnosis to therapeutics breakthroughs. World J Exp Med 2026; 16(1): 112270
URL: https://www.wjgnet.com/2220-315x/full/v16/i1/112270.htm
DOI: https://dx.doi.org/10.5493/wjem.v16.i1.112270

Bouziane M, Moufid O, Habbal R. Cardiac amyloidosis: From diagnosis to therapeutics breakthroughs. World J Exp Med 2026; 16(1): 112270 [PMID: 41883450 DOI: 10.5493/wjem.v16.i1.112270]

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