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©The Author(s) 2025.
World J Exp Med. Dec 20, 2025; 15(4): 114554
Published online Dec 20, 2025. doi: 10.5493/wjem.v15.i4.114554
Table 4 Clinical applications of hypnosis in pediatric medicine with degree of recommendation
Medical domain
Specific applications & conditions
Degree of recommendation
Pain managementAcute procedural pain: Venipuncture, intravenous cannulation, lumbar puncture, bone marrow aspiration, burn dressing, dental procedures, post-operative pain, suturing, catheterization. Chronic/recurrent pain: Functional abdominal pain, migraines, tension headaches, fibromyalgia, sickle cell crises, juvenile arthritis, CRPS, neuropathic, and phantom painA
Anxiety & phobiasProcedural anxiety, preoperative fear, needle phobia (trypanophobia), dental phobia, “white coat” syndrome, generalized anxiety, separation anxiety, social and performance anxiety, panic attacksA
OncologyPain from procedures and treatment, chemotherapy-induced nausea and vomiting (especially anticipatory), procedural anxiety, fatigue, emotional coping, and appetite improvementA
GastroenterologyIBS, functional abdominal pain, dyspepsia, cyclic vomiting syndrome, functional nausea, encopresis, constipation, rumination syndrome, IBD-related pain, and anxietyB
Neurology/behavioral healthTics, Tourette's, habit cough, PNES, FND, sleep disorders, nocturnal enuresis, anger and impulse control issues, and bruxismB
DermatologyAtopic dermatitis (itch-scratch cycle), warts, trichotillomania, excoriation disorder, psoriasis, and neurodermatitisB
PulmonologyAsthma-related anxiety, hyperventilation syndrome, procedural anxiety in cystic fibrosis, and treatment adherence (e.g., nebulizers/inhalers)B
General health & wellnessStress management, focus and concentration (non-ADHD specific), self-esteem, habit cessation (e.g., nail biting), body image, sleep hygiene, relaxation training, and reinforcement of a healthy lifestyleB
UrologyNocturnal enuresis, functional voiding disorders, urgency/frequency syndromes, and anxiety during urodynamic testingB
Rehabilitation & physical therapyEnhancing pain tolerance during therapy, improving motivation, managing movement fear, and recovering from injuryC
Endocrinology & metabolismSupport for insulin injections, blood glucose monitoring, and coping with chronic illness stress (e.g., diabetes)C


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