Lack of cytoplasmic expression of a new marker programmed cell death ligand-1 in tumor cells is significant

Figure 6 Lack of cytoplasmic programmed cell death protein 1 ligand 1 expression in tumor cells. A: Lack of cytoplasmic programmed cell death protein 1 ligand 1 (cPDCD1 LG1) expression at the invasive edge of the tumor [in < 20% of tumor cells (TCs)]; B: Lack of cPDCD1 LG1 expression in the central part of the tumor (in ≥ 20% of the TCs); C: Lack of cPDCD1 LG1 expression in most of the tumor parenchyma; D: Severe basophilia and elongated shape of the TC nuclei in the absence of cPDCD1 LG1 expression. Staining with anti-PDCD1 LG1 antibodies, A-C: Scale bar is 200 μm, D: Scale bar is 50 μm.