Immunohistochemical expression of epithelial mesenchymal transition proteins ZEB1 and E-cadherin in oral leukoplakia and oral squamous cell carcinoma

Table 3 Comparison of zinc-finger E-box-binding homeobox 1 expression in connective tissue with respect to intensity and percentage scores among two study groups (oral epithelial dysplasia and oral squamous cell carcinoma) by Kruskal Wallis analysis of variance

ZEB1 expression in connective tissue	Intensity				Percentage of positivity
	0	1	2	Value	0	1	2	3	Value
OED (n = 30)	0	2	28	-	0	1	6	23	-
OSCC (n = 30)	1	18	11	P = 0.0038a	1	20	4	5	P = 0.0001b

^aP < 0.05.

^bP < 0.01.

Intensity: 0: Negative, 1: Mild, 2: Moderate. Location: 0: Absent, 1: Membrane, 2: Cytoplasm + nucleus, 3: Cytoplasm. Percentage: 0: Absent, 1: 1%-25%, 2: 25%-50%, 3: > 50%. OED: Oral epithelial dysplasia; OSCC: Oral squamous cell carcinoma; ZEB1: Zinc-finger E-box-binding homeobox 1.