Gut microbiota and metabolic-associated steatosis liver disease: Unveiling mechanisms and opportunities for therapeutic intervention

doi:10.5493/wjem.v15.i4.107316

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Exp Med. Dec 20, 2025; 15(4): 107316
Published online Dec 20, 2025. doi: 10.5493/wjem.v15.i4.107316

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Figure 3 The bidirectional gut–liver communication through bile acids. Bidirectional gut–liver communication illustrates how microbial metabolites and endotoxins disrupt the intestinal barrier and drive hepatic inflammation, while bile acids regulate gut homeostasis.

Citation: Rusman RD, Akil F, Parewangi ML, Daud NA, Bachtiar R, Kusuma SH, Rifai A. Gut microbiota and metabolic-associated steatosis liver disease: Unveiling mechanisms and opportunities for therapeutic intervention. World J Exp Med 2025; 15(4): 107316
URL: https://www.wjgnet.com/2220-315x/full/v15/i4/107316.htm
DOI: https://dx.doi.org/10.5493/wjem.v15.i4.107316

Rusman RD, Akil F, Parewangi ML, Daud NA, Bachtiar R, Kusuma SH, Rifai A. Gut microbiota and metabolic-associated steatosis liver disease: Unveiling mechanisms and opportunities for therapeutic intervention. World J Exp Med 2025; 15(4): 107316 [PMID: 41497693 DOI: 10.5493/wjem.v15.i4.107316]

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