Integrative review of the gut microbiome’s role in pain management for orthopaedic conditions

doi:10.5493/wjem.v15.i2.102969

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Jun 20, 2025 (publication date) through May 1, 2025

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Exp Med. Jun 20, 2025; 15(2): 102969
Published online Jun 20, 2025. doi: 10.5493/wjem.v15.i2.102969

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Figure 2 Osteoimmunology of degenerative joint disease resulting in arthritis. TNF: Tumor necrosis factor; MCP: Monocyte chemoattractant protein; IL: Interleukin; MMP: Matrix metalloproteinase; PRR: Pattern recognition receptor; RAGE: Receptor for advanced glycation end products; TLR: Toll-like receptor; HSP: Heat shock protein; HMGB: High mobility group box.

Citation: Jeyaraman N, Jeyaraman M, Dhanpal P, Ramasubramanian S, Nallakumarasamy A, Muthu S, Santos GS, da Fonseca LF, Lana JF. Integrative review of the gut microbiome’s role in pain management for orthopaedic conditions. World J Exp Med 2025; 15(2): 102969
URL: https://www.wjgnet.com/2220-315x/full/v15/i2/102969.htm
DOI: https://dx.doi.org/10.5493/wjem.v15.i2.102969