Establishment and characterization of a new human gallbladder cancer cell line, OCUG-2

Figure 4 Invasion ability of OCUG-2 cells and insulin-like growth factor 1 receptor staining of gall bladder tumors. A: Effects of various targeted drugs on the invasion ability of OCUG-2 cells. Invasion ratio of OCUG-2 cells post-treatment compared to controls. Photograph (200 ×) of OCUG-2 invasion cells treated with control or SU11274; B: Immunohistochemical staining of insulin-like growth factor 1 receptor (IGF1R). IGF1R expression was found on cancer cell membrane. Scale bar, 100 μm. Kaplan-Meier survival analysis comparing overall survival and disease-free survival in IGF1R-positive and IGF1R-negative gallbladder cancer patients. ^aP < 0.05, ^bP < 0.01, and ^cP < 0.001.