Differential diagnosis and management of immune checkpoint inhibitor-induced colitis: A comprehensive review

Figure 3 Representative images of medication-induced colitis (Hematoxylin and eosin). A: Ring mitosis caused by docetaxel in duodenum (400 ×); B: Small bowel diaphragm. Fibrotic submucosa protrudes into the intestinal lumen and forms a diaphragm (8 ×); C: Low magnification view of mycophenolate mofetil-induced colitis. (100 ×); D: Higher magnification view of mycophenolate mofetil-induced colitis. There is an inflammatory cell infiltrate consisting of lymphocytes, plasma cells and eosinophils in the lamina propria with neutrophilic cryptitis (400 ×). Yellow sign notes a ring mitosis.