Review
Copyright ©The Author(s) 2015.
World J Exp Med. May 20, 2015; 5(2): 40-49
Published online May 20, 2015. doi: 10.5493/wjem.v5.i2.40
Figure 2
Figure 2 Endothelial-derived signals maintain expression of PDX-1 and promote pancreatic endocrine differentiation. Once the aorta is forming, aortic ECs (AECs) interact closely with FG/DE cells that maintain expression of PDX-1 and form the dorsal pancreatic bud (DPB). ECs: Endothelial cells; DE: Definitive endoderm; FG: Foregut; PDX: Pancreatic and duodenal homeobox.