Review
Copyright ©The Author(s) 2015.
World J Exp Med. May 20, 2015; 5(2): 64-76
Published online May 20, 2015. doi: 10.5493/wjem.v5.i2.64
Table 2 Nitric oxide and its effect in pathologies
DiseasePathogenesisRef.
Autoimmune diseases
Appearance of neo-epitopes[29,30,96-98,101,123, 126,130]
Disruption of physical barriers
Amelioration of pathological status
Metabolic disease
Deregulated accumulation of proteins or their abnormal modification[109,110,115,119,120]
Cancer
Establishment of an immune suppressive environment[140-142,147,151,152, 155,157,160]
Alteration in DNA repair mechanisms