Changes in the metabolism of axillary lymph node cells as a predictor of regional metastasis in breast cancer

doi:10.5493/wjem.125128

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World Journal of Experimental Medicine

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2220-315X

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World J Exp Med. Sep 20, 2026; 16(3): 125128
Published online Sep 20, 2026. doi: 10.5493/wjem.125128

Table 13 Correlations of indicators of delayed luminescence of erythrosine with C-X-C motif chemokine receptor 4 expression

	Spearman-R	t(N-2)	P value
Indicator 1
CXCR4 expression in the LN sinuses	-0.053527	-0.37903	0.706268
CXCR4 expression in the LN follicles	-0.221404	-1.60540	0.114703
CXCR4 expression in the LN cortex	-0.103418	-0.73522	0.465643
CXCR4 expression in the LN medulla	-0.019459	-0.13762	0.891092
Indicator 2
CXCR4 expression in the LN sinuses	-0.212379	-1.53681	0.130645
CXCR4 expression in the LN follicles	0.255859	1.87149	0.067134
CXCR4 expression in the LN cortex	-0.234264	-1.70391	0.094605
CXCR4 expression in the LN medulla	0.207313	1.49848	0.140297
Indicator 3
CXCR4 expression in the LN sinuses	-0.072580	-0.51458	0.609117
CXCR4 expression in the LN follicles	-0.245256	-1.78886	0.079696
CXCR4 expression in the LN cortex	-0.082620	-0.58621	0.560369
CXCR4 expression in the LN medulla	-0.139046	-0.99285	0.325566
Indicator 4
CXCR4 expression in the LN sinuses	-0.099432	-0.70659	0.483101
CXCR4 expression in the LN follicles	-0.055230	-0.39113	0.697363
CXCR4 expression in the LN cortex	-0.035307	-0.24981	0.803757
CXCR4 expression in the LN medulla	0.103639	0.73681	0.464684
Indicator 5
CXCR4 expression in the LN sinuses	0.003261	0.02306	0.981692
CXCR4 expression in the LN follicles	0.535508	4.48369	0.000043^a
CXCR4 expression in the LN cortex	-0.016864	-0.11926	0.905546
CXCR4 expression in the LN medulla	0.137211	0.97949	0.332054
Indicator 6
CXCR4 expression in the LN sinuses	0.129308	0.92209	0.360912
CXCR4 expression in the LN follicles	0.120409	0.85766	0.395171
CXCR4 expression in the LN cortex	0.057093	0.40437	0.687667
CXCR4 expression in the LN medulla	0.053138	0.37627	0.708306

^aP value < 0.0250 is considered significant.

t(N-2): The value of the Student’s t-test for the number of degrees of freedom n-2. CXCR4: C-X-C motif chemokine receptor 4; LN: Lymph node.

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Citation: Senchukova MA, Ishemgulov AT, Letuta SN, Saidler NV, Tagabilev DG. Changes in the metabolism of axillary lymph node cells as a predictor of regional metastasis in breast cancer. World J Exp Med 2026; 16(3): 125128
URL: https://www.wjgnet.com/2220-315X/full/v16/i3/125128.htm
DOI: https://dx.doi.org/10.5493/wjem.125128

Senchukova MA, Ishemgulov AT, Letuta SN, Saidler NV, Tagabilev DG. Changes in the metabolism of axillary lymph node cells as a predictor of regional metastasis in breast cancer. World J Exp Med 2026; 16(3): 125128 [DOI: 10.5493/wjem.125128]

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