Evaluation of short and long-term laboratory and instrumental findings in COVID-19 patients hospitalized in Tuscany

Table 1 Relative risks for the main blood tests in the study population of the need for oxygen therapy or of forced expiratory volume in one second/forced vital capacity < 70% during follow-up Source: Regional Health Agency Sprint data

Blood tests	Level	Raw RR				RR adjusted for age and gender								RRs adjusted for age and gender RRs adjusted for age. gender. days after discharge
		RR	Min	Max	P value	RR		Min		Max		P value		RR	Min	Max	P value
Alteration of liver enzymes (aspartate aminotransferase, alanine transaminase, Gamma-gamma-glutamyl transferase)	None
	1 or more impaired during hospitalization	0.63	0.36	1.09	0.099	0.66		0.38		1.15		0.144		0.70	0.40	1.22	0.207
	Altered at discharge	1.61	1.09	2.39	0.017	1.61		1.07		2.42		0.021		1.55	1.03	2.32	0.034
D-Dimer	None	1.00				1.00								1.00
	1 or more impaired during hospitalization	0.73	0.19	2.85	0.652	0.65		0.16		2.59		0.543		0.74	0.18	3.09	0.684
	Altered at discharge	0.76	0.46	1.23	0.263	0.76		0.47		1.23		0.264		0.77	0.46	1.30	0.328
Hematocrit	None	1.00				1.00								1.00
	1 or more impaired during hospitalization	0.92	0.53	1.57	0.751	0.76		0.46		1.28		0.305		0.77	0.52	1.12	0.169
	Altered at discharge	0.55	0.37	0.83	0.005	0.46		0.30		0.68		0.000		0.47	0.33	0.67	0.000
Hemoglobin	None	1.00				1.00								1.00
	1 or more impaired during hospitalization	1.13	0.71	1.79	0.610	0.84		0.53		1.33		0.464		0.86	0.56	1.33	0.505
	Altered at discharge	0.73	0.50	1.07	0.108	0.58		0.39		0.86		0.007		0.60	0.41	0.89	0.011
Ferritin	None	1.00				1.00								1.00
	1 or more impaired during hospitalization
	Altered at discharge	1.12	0.65	1.92	0.689	1.09		0.64		1.85		0.765		0.99	0.58	1.70	0.979
Glomerular filtration rate	None	1.00				1.00								1.00
	1 or more impaired during hospitalization	0.83	0.45	1.54	0.563	0.52		0.28		0.98		0.043		0.45	0.25	0.82	0.009
	Altered at discharge	1.30	0.76	2.20	0.339	0.84		0.50		1.43		0.531		0.75	0.48	1.18	0.213
White globules	None	1.00					1.00							1.00
	1 or more impaired during hospitalization	1.12	0.68	1.82	0.661		0.96		0.60		1.56		0.884	0.91	0.58	1.42	0.674
	Altered at discharge	1.01	0.53	1.91	0.984		0.98		0.53		1.84		0.960	0.92	0.52	1.65	0.789
Red cells	None	1.00					1.00							1.00
	1 or more impaired during hospitalization	0.97	0.58	1.62	0.904		0.83		0.50		1.35		0.451	0.85	0.53	1.35	0.484
	Altered at discharge	0.76	0.52	1.12	0.168		0.59		0.40		0.87		0.008	0.59	0.41	0.87	0.007
Lymphocytes	None	1.00					1.00							1.00
	1 or more impaired during hospitalization	0.62	0.33	1.17	0.143		0.55		0.30		1.02		0.058	0.57	0.31	1.05	0.070
	Altered at discharge	0.87	0.49	1.54	0.635		0.55		0.31		0.97		0.037	0.56	0.32	0.99	0.045
Monocytes	None	1.00					1.00							1.00
	1 or more impaired during hospitalization	1.05	0.61	1.79	0.871		1.04		0.61		1.77		0.883	1.05	0.62	1.79	0.850
	Altered at discharge	1.75	0.93	3.32	0.085		1.53		0.82		2.86		0.180	1.69	0.89	3.21	0.109
Neutrophils	None	1.00					1.00							1.00
	1 or more impaired during hospitalization	0.97	0.55	1.69	0.907		0.83		0.49		1.43		0.507	0.81	0.48	1.39	0.451
	Altered at discharge	0.75	0.41	1.38	0.351		0.50		0.27		0.92		0.026	0.42	0.23	0.77	0.004
Platelets	None	1.00					1.00							1.00
	1 or more impaired during hospitalization	0.70	0.39	1.26	0.237		0.63		0.36		1.12		0.118	0.64	0.36	1.13	0.126
	Altered at discharge	0.74	0.34	1.57	0.429		0.69		0.33		1.43		0.317	0.73	0.36	1.50	0.392
Protein C reactive	None	1.00					1.00							1.00
	1 or more impaired during hospitalization	2.05	0.50	8.43	0.319		1.56		0.39		6.18		0.529	1.53	0.39	6.09	0.544
	Altered at discharge	3.44	0.88	13.50	0.077		2.58		0.68		9.78		0.164	2.31	0.61	8.79	0.219

Max: Maximum; Min: Minimum; RR: Relative risk.