Use of intralesional collagenase in the treatment of peyronie’s disease: A review

Table 4 Study outcomes

Ref.	Outcome	Oxford Centre for Evidence-Based
		Medicine 2011 Levels of Evidence
Gelbard et al[22]	Improvement seen in 20 patients (4 had plaque disappearance, 16 had curvature decrease by 20%-100%)	2
Gelbard et al[23]	Overall, 36% responsed to treatment. Improvement greatest in patients with lesser degree of pre-treatment curvature	2
Jordan[24]	Significant mean changes from baseline angular deviation and plaque width at 3, 6, and 9 mo	2
Gelbard et al[25]	Improved penile curvature (29.7% vs 11.0%, P < 0.05 ) and patient reported bother scores for treatment group vs placebo	1
Gelbard et al[26]	Improved penile curvature (34% vs 18%, P < 0.0001) and patient reported symtom bother score for treatment group vs placebo	1