Ocular renin-angiotensin system with special reference in the anterior part of the eye

Table 2 Renin-angiotensin system components in ciliary body, non-pigmented ciliary epithelium, lens, vitreous, optic nerve head and sclera

RAS component	Ciliary body/non-pigmented ciliary epithelium		Lens	Vitreous	Optic nerve head	Sclera
Prorenin	Sramek et al[109]	White et al[98]		Danser et al[99]		White et al[98]
	Danser et al[99]			Wallow et al[110]
	Wallow et al[110]
	Berka et al[111]
Renin	Berka et al[111]	White et al[98]				White et al[98]
AGT	Sramek et al[112]			Sramek et al[112]
ACE1	Igic et al[113]	Savaskan et al[13]		Ferrari-Dileo et al[106]	Ferrari-Dileo et al[106]	White et al[98]
	Ferrari-Dileo et al[106]	White et al[98]		Nakanishi et al[114]
	Sramek et al[112]			Ishizaki et al[115]
				Aydin et al[105]
ACE2
Ang I	Danser et al[14]
Ang II	Danser et al[14]	Senanayake et al[108]		Senanayake et al[108]	Savaskan et al[13]
	Savaskan et al[13]
Ang(1–7)	Vaajanen et al[95]	Vaajanen et al[95]

Table modified and updated from the table published by Giese et Speth, 2014. ACE1, -2: Angiotensin converting enzyme 1, -2; AGT: Angiotensinogen; AngI, -II: Angiotensin I, -II; Ang(1–7): Angiotensin (1–7); RAS: Renin-angiotensin system.